The agrochemicals and seeds giant, Syngenta, says 130 jobs are to be cut in its research and technology departments in Switzerland.
The company's site in Basel will lose 100 jobs out of a current workforce of 500. As part of its restructuring plans, Syngenta announced on Wednesday that Basel will in the future concentrate on chemical plant protection.
Another 30 jobs are to go at the group's site in Stein in canton Aargau.
The plans are part of a reorganisation that will see another 370 research and technology jobs cut at other plants in Europe and the United States.
Syngenta was formed by the merger of the agribusinesses of Novartis and AstraZeneca. It is the world's largest crop protection company and number three in commercial seeds.
It began trading on the Zurich stock exchange last week.
swissinfo with agencies