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EU approves Roche drug Columvi for lymphoma treatment

Roche: EU approves Columvi for lymphoma treatment
Roche: EU approves Columvi for lymphoma treatment Keystone-SDA

The European Commission has approved Roche's Columvi as the first bispecific antibody for the treatment of diffuse large B-cell lymphoma after initial therapy, the pharmaceutical giant announced on Monday.

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The approval is based on the result of the phase III Starglo trial, during which Columvi – combined with Gemcitabine and oxaliplatin (GemOx) – demonstrated a “statistically and clinically significant improvement in survival” compared to other treatments, Roche explained.

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Relapsed or refractory diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer with a high risk of progression, which means that urgent and effective treatments are needed. In primary analyses, a 41% reduction in the risk of death was found among patients treated with Columvi and GemOx.

Translated from Italian by DeepL/ts

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